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Cannabis Wiki CannaBasics 5 days ago / London, Ontario


Cloning marijuana

Cloning is a technique of growing marijuana plants in order to multiply them. In cloning, only female cannabis plants are used. As the name suggests, the cloned plants will share genetics. If you're interested in learning more about how to clone marijuana plants follow the link below.

Read the full guide and more at Cannabis.Wiki.

Related comments

JADEO CannaBasics 2 weeks ago / Toronto, Ontario


{VIDEO} Is It Safer To Smoke Weed Than Smoke Cigarettes?

We take a quick look at the difference between smoking cannabis and smoking cigarettes.

Check out the full article at: https://cannabis.wiki/cannabis...


-

The views and opinions expressed in this video are of the presenter and do not necessarily reflect the official policies or positions of JADEO.

JADEO makes no representations or warranties of any kind, express or implied, about the completeness, accuracy, reliability or suitability with respect to any content contained within the video.

JADEO urges you to consult with a qualified physician for consultation, diagnosis and/or treatment plans with respect to your medical condition(s) and/or wellness goals.

-



Stay informed. Stay connected.
#WeAreJadeo


Related comments

  • From Burge

    Sweet video

Cannabis Wiki Strains & Growing 1 month ago / London, Ontario


Complete guide to common cannabis pests and how to treat them

If you're curious about all the different pests your cannabis plants might bring or are looking to identify a particular insect, you've come to the right place. Follow along this guide to learn about some of the most common cannabis plant pests and how to get rid of them.


Check out the full guide and more at Cannabis Wiki.


Related comments

  • From Connor Christine

    Good to know.

  • From 22

    You should try interviewing the Master Grower Derek Pedro.... he has LOTS of knowledge in his head..

Cannabis Wiki Strains & Growing 1 month ago / London, Ontario


Here’s how to prevent deformed marijuana leaves

If you've ever had cannabis plants with leaves that have curled or become disheveled in some way, you know how frustrating it can be. So what is that's causing your plants to grow awry? Read on to learn some easily preventable causes of theses phenomenon.


Check out the full guide and more at Cannabis Wiki.

Related comments

Cannabis Wiki CannaBasics 1 month ago / London, Ontario


Making Cannabutter: Top 3 Cannabutter recipes

There are many benefits to making your very own cannabutter at home. Not only can you be 100% sure of the ingredients but it’s really easy!

Cannabutter is also one of the most versatile and healthy ways to ingest THC and CBD. No smoke or harmful chemicals and all the benefits. Cannabutter is used as the base of most edibles. From brownies and cookies to sauces and spreads.

Check out the top 3 cannabutter recipes at Cannabis Wiki

Related comments

  • From Janelle Simone

    ooooh this is good!

  • From Kenneth Joaquin

    Definitely trying this out.

Advertisement

BahaqueenM CannaBasics 2 months ago / Ontario

I'm pretty new to cannabis and been researching how to make homemade cannabutter. I came across suggestions of making it in an instant pot - which is supposed to be a quicker process sans the smell. This how-to video makes it seem pretty easy. Has anybody tried this or know anybody who has? https://www.youtube.com/watch?v=V6AQplp6YUg&has_verified=1

x

x

How to Make Cannabis Butter in an Instant Pot

YouTube

Step by step instructions: https://goo.gl/CgWr2R Interestingly, making weed butter in a pressure cooker is pretty fast. It won't take you longer than a few hours, unlike doing it on a stovetop, for example. And you'll be dealing with hardly any mess - the most exciting part of this recipe.

http://www.youtube.com/watch?v=V6AQplp6YUg

Related comments

  • From Janelle Simone

    I have an instant pot and have heard whispers of using it for making cannabutter. Thanks for sharing the how-to video. I just may try this!

  • From Brianne Campbell

    Ooh wow! I'm wondering if this would work with my Crock Pot too!
    *googles 'how to make cannabis butter in crock pot'*

JADEO CannaBasics 2 months ago / Toronto, Ontario


Top 3 Books That Break The Stigma

Life after prohibition is an uncharted landscape with lots of new opportunities to shift our culture to one with less stigma around the use of the cannabis plant. JADEO members may represent those of us who are pro-legalization, but what if you find yourself in conversations with prohibitionists? Having a very good grasp on the context of our new freedom with legalization could help you speak with any of these individuals, or with someone you love who could benefit from medicinal cannabis but fears how others may judge them. There is an entire history of cannabis to put into perspective when being an advocate or an informed friend, so we wanted to showcase a few books to pick up which help break the stigma around this important topic for JADEO members.

Busted

An Illustrated History of Drug Prohibition in Canada
By Susan Boyd

"Busted" by Susan Boyd

One of the lesser known books on cannabis topped our list because it’s specific to the history of cannabis prohibition in Canada. Busted is an illustrated history of Canadian drug prohibition that provides insights on the resistance to that prohibition. “Reproducing over 170 archival and contemporary drawings, paintings, photographs, film stills and official documents from the 1700s to the present, Susan Boyd shows how Canada’s drug prohibition policies evolved and were shaped by race, class and gender discrimination.” Her beautifully designed book demonstrates through a look into the history how prohibition and criminalization produces harm rather than benefits. The book acknowledges the arrest of thousands of Canadians each year for cannabis-related offences, and the current drug overdose crisis.

“Busted is a book that should be read by all those who wish to understand our convoluted drug policy. Combining historic and modern graphics with scientific facts, the book allows readers to grasp the insanity of drug laws.”

— Senator Larry Campbell

Brave New Weed: Adventures into the Uncharted World of Cannabis

By Joe Dolce

"Brave New World" by Joe Dolce

In Brave New Weed, former editor-in-chief of Details and Star, and author Joe Dolce, goes to Amsterdam, Israel, California, and Colorado, where he “skillfully unfolds the odd, shocking, and wildly funny history of this complex plant.” As he travels the globe he "tears down the cannabis closet" in an attempt to demystify this new frontier, seeking answers to the questions we didn’t know we should ask.

Looking back at the war on cannabis which has been waged in the United States since the early years of the twentieth century, society has undergone a massive shift in perspective since legalization has begun to catch fire, that is allowing us all to reconsider our beliefs. Dolce traces its history and possible future as he investigates the social, medical, legal, and cultural ramifications of this surprisingly versatile plant. As a result he paints “a fresh and much-needed portrait of cannabis, our changing attitudes toward it, and the brave new direction science and cultural acceptance are leading us.”

The Cannabis Manifesto

by Steve DeAngelo

"The Cannabis Manifesto" - by Steve DeANGELO

Steve DeAngelo, the founder of Harborside Health Center, the world's largest medical-cannabis dispensary, presents a compelling case for cannabis as a wellness catalyst that must become broadly legalized. In The Cannabis Manifesto he shares his view that there is no such thing as recreational cannabis use, challenging readers to rethink everything they thought they knew about cannabis.

A compelling overview of the state of cannabis today, DeAngelo explains how “prohibition has warped our most precious institutions—from the family, to the workplace, to the doctor’s office and the courtroom.” His book answers essential questions about the plant, using extensive research to fuel a thoughtful discussion about cannabis science and law, as well as its biological, mental, and spiritual effects on human beings.

Comment below and let us know your fave books for breaking the stigma.

Related comments

JADEO CannaBasics 3 months ago / Toronto, Ontario

Get lifted, have fun, and most importantly BE SAFE!

x

x

Related comments

  • From BahaqueenM

    Happy 420!

  • From Burge

    Happy 420 !!! ✌

  • From Sativasky

    Have a bless 420 ❤️✌

Sawyer Burns CannaBasics 3 months ago / Winnipeg, Manitoba

Question does anybody journal/track their weed use? Would you recommend doing it?

x

x

Related comments

  • From Sativasky

    Yes, yes and YES! I started doing this about 2 years back, and it has continued to be a part of my routine. I typically use it for the reason of going back for referrals. For example, it lets me look back into the strains I've used and use some good judgment on my next session. I highly recommend doing it!

JADEO CannaBasics 3 months ago / Toronto, Ontario


The Entourage Effect: A Closer Look

There’s been a lot of buzz lately about a phenomenon called “the entourage effect,” but what is it?

The idea behind this effect is that when we combine compounds in their natural state we don’t end up with the sum of the parts but rather a multiplying effect. With cannabis, thousands of natural compounds within the plant interact together and with the human body to produce a more meaningful effect than what you’d experience with any single one of the compounds used alone.

This term “entourage effect” was only first introduced around the year 2000, by the Israeli chemist who first who first discovered THC as the main psychoactive component of cannabis. It’s discovery helps explain why different cannabis strains may have different effects depending on the individual. Since strains can differ vastly in their chemical profiles, they can cause an equally vast number of experiences.

Lack of clinical trial research has given rise to critics of the entourage effect who claim that it does not exist, but in fact, it’s very concept is rooted in the centuries-old practice of whole plant medicine. The basic concept is that the chemical compounds found in medicinal plants work together to help that plant to offer its own power to provide healing.

The entourage effect

In the original study, Rafael Mechoulam Mechoulam and fellow chemist Shimon Ben-Shabat examined the interactions between compounds in the cannabis plant and found that certain cannabinoids, which had no effect on their own, could be used to help other cannabinoids in the plant to work more effectively. Other studies since back this initial finding, yet the concept of “the entourage effect” somewhat surprisingly remains a debated topic.

There’s no debate however to Dr. Ethan Russo, who is a Seattle based board certified neurologist and has done immense research on psycho-pharmacology. Former president of the International Cannabinoid Research Society and a former Chairman for the International Association for Cannabinoid Medicines, after 20 years of clinical practice, Dr. Russo took a full-time consulting position with a company out of Britain that develops cannabis based pharmaceuticals.

Dr. Russo is recognized internationally for his research on cannabis compounds and their effects in the body. His research found that “complementary pharmacological activities that may strengthen and broaden clinical applications and improve the therapeutic index of cannabis extracts.” Through these findings he discovered “synergistic effects” between different compounds that enhance and boost each other when combined.

In this we recognize isolated cannabinoids as if each has a list of specific effects. All of Dr. Russo’s research suggests that these effects can be mitigated, or enhanced, when they are paired with other chemical compounds that naturally appear in whole-plant cannabis.

While THC and CBD may be the most famous cannabinoids, they are by no means the only ones. In fact, they’re just two among many important players within the cannabis plant that work together to produce a number of potential therapeutic effects. There are at least 113 known cannabinoids found in cannabis, which bind to receptors in the human body’s endocannabinoid system, specifically the CB1 and CB2 receptors.

If you closely inspect your cannabis flowers, you’ll notice they’re enrobed in a layer of crystal resin that’s sticky to the touch. These crystals house thousands of compounds, including these cannabinoids and a number of terpenes and flavonoids. If you take pure THC, which we know is the main psychoactive ingredient in cannabis, you’ll experience “a high that has no specific character, so that seems boring,” says Mowgli Holmes, a geneticist and founder of a cannabis genetics company Phylos Bioscience. What gives cannabis “character,” in his similar view, are the hundreds of other chemicals it contains.

So what are the hundreds of other chemicals cannabis can contain other than cannabinoids? Dr. Russo examined the benefits of using products containing certain cannabinoids with specific terpenes. Terpenes are essential oils that naturally occur and give cannabis plants distinctive aromas and flavors. His research revealed that terpenes “could produce synergy with respect to treatment of pain, inflammation, depression, anxiety, addiction, epilepsy, cancer, fungal and bacterial infections.”

There is still much research to be done however to determine how all these fascinating chemicals react on a molecular level. In a 2011 review published in the British Journal of Pharmacology, chemists found similar interactions between cannabinoids and terpenes.

It’s believed that when the terpenes remain in a cannabis based product, the benefits are magnified. Researchers discovered that a terpene, linalool, combined with a cannabinoid like CBD, could be used as an effective anti-anxiety medication. Whereas combining linalool with THC makes for a potent sedative, or combining the terpene alpha-pinene with THC helps to retain acetylcholine (a molecule that aids in memory retention) and could help to mitigate the short-term memory loss caused by THC.

The power of scent in the entourage effect seems like a never ending list of fascinating molecular combinations. Limonene is an energizing terpene that can alleviate depression symptoms. Beta- Caryophyllene is powerful in reducing inflammation throughout the body, including the gastrointestinal system. Myrcene has sedative effects which promote calmness and provide relief from anxiety. Linalool is also an anti-anxiety and capable of acting as an anti-microbial. Pinene combats cognitive and memory issues by increasing focus. Multiple terpenes can be used in conjunction to treat a variety of issues in a single dose.

So while whole plant products with terpenes and full spectrum cannabinoids have high efficiency and are more potent than using an isolated compound, we see THC and CBD isolated in clinically approved medications. The reason for this is largely due to the regulatory standards that surround modern medicine. In essence, isolated compounds are much easier to dose, measure and track than a compound found naturally in a plant.

Medicines which are approved in the U.S. by the FDA have to be standardized, meaning that every dose must contain an exact amount of THC, something which can be difficult to guarantee in smokable cannabis, which usually comes with a THC content range rather than an exact measurement. This is the same as what we see prescribed by most doctors in Canada, but thankfully that is changing as legalization pushes the advances of medicinal cannabis.

Isolating constituents from the rest of the components that make up the whole-cannabis plant may offer MDs precision in prescribing, but most anecdotal evidence proves the endocannabinoid system responds more favourably to a full flower cannabis experience.

Consider the drug Marinol, a synthetic form of THC available since the 1980s. It is known to be a good appetite stimulant, but it’s also known to make patients high and paranoid. “When you just stimulate the CB1 receptor with this pure molecule, it's very intoxicating and patients don't tolerate it very well,” says Adie Wilson-Poe, who researches cannabis for pain management at Washington University in St. Louis.

Drugs like Sativex, which combines THC with CBD, or even pure cannabis flower or extracts, and is known to be tolerated by patients much better. “We specifically see that CBD protects against the paranoia and anxiety and the racing heart that THC produces,” Wilson-Poe says.

For smokers, flower vapers, or those making their own edibles by infusing flower into fats, what you will be experience is essentially the entourage effect. In our recent #wcw feature with Katrina Malmqvist of Gräs, she explained how the entourage effect is present in her fat bomb micro dose edibles.

"Since cannabinoids are fat soluble, I began infusing cannabis into organic coconut oil, which I found to be the best carrier. What I discovered was what we call the entourage effect; a microdose with full flower infusion of just 3mg was giving such a beautiful effect. It is long lasting, and delivers this slow, wonderful elevation that I found really helped me deal with some postpartum anxiety I was experiencing."

Unlike the isolated compounds, the full flower infuses into the carrier oils and is delivered to the body to produce a “next-level” high. Find this fascinating? So do we. To educate yourself more on microdosing, terpenes or the endocannabinoid system visit our special interest groups.

Related comments

Janelle Simone CannaBasics 3 months ago / Scarborough, Ontario

It allows me to relax, annnnnnd get more restful sleep! Why do you love it?

x

x

Related comments

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Fabrizio Rossi CannaBasics 3 months ago / Vancouver, British Columbia


2019 The year not for the faint of heart in Cannabis.

2018 was the end of prohibition and definitely changed the landscape of our society in several ways, not only in Canada but on the worldwide stage.

Several countries around the world have opened the doors to medicinal Cannabis, but specifically countries in Asia is proof the winds of change are on the horizon and within the western hemisphere countries like Mexico are well on their way to legalization. And let’s not forget the Hemp bill in the US changing the CBD category. We are in for another amazing year in 2019.

2018 definitely had a few speed bumps along the way for Cannabis in Canada but we finished the first year of legalization in a good spot to start 2019.

Retail Provincial frameworks are visible in all provinces. Even though we may not agree with some provincial regulations, we have a starting point, and with days from Vancouver opening its first retail outlet this category will be an exciting one to observe.

Supply shortages are definitely an everyday story in all provinces and with some suppliers taking advantage of supply and demand and charging as much as $13 per gram, this made things even more interesting. But I do believe most LPs are moving forward with true forecasting initiatives to make sure the production facilities are optimized within their supply chain.

Micro Cultivation movement is well on their way with over 30 applications already submitted in the system. The "authentic craft cannabis" segment will be a great one to observe this year as the Master growers showcase their passion, strains and abilities, and with regulations allowing new players to bring new strains no questions asked, we should see some exciting new things by the end of 2019.

Edibles the new opportunity for 2019 for processing facilities to make a name for themselves is definitely one of my favorites. This will be a huge piece of the market with edibles, drinkables and everything else in between joining the market.

Market reports and sales results will be not for the faint of heart to watch as the "story" won’t be as important as the true results and category leaders and innovators surface to claim their titles.

Overall, an exciting year ahead for all of us but as always I want to take a moment to say thank you to all of you for sharing this exciting industry with me and each other. Yes, we all compete with each other in one way or another, but most of us share wins and challenges with each other as we are all growing, learning and paving the way to create a great, responsible, environment friendly industry for a better medicinal and recreational Cannabis.

Related comments

  • From Janelle Simone

    Agreed! There have been a few bumps but we're doing something that has never been done on this level before so this is to be expected. What is exciting is how the industry is learning and progressing. 2019 and beyond will definitely see growth and opportunity.

Cannabis Wiki CannaBasics 5 days ago / London, Ontario


Cloning marijuana

Cloning is a technique of growing marijuana plants in order to multiply them. In cloning, only female cannabis plants are used. As the name suggests, the cloned plants will share genetics. If you're interested in learning more about how to clone marijuana plants follow the link below.

Read the full guide and more at Cannabis.Wiki.

Related comments

JADEO CannaBasics 2 weeks ago / Toronto, Ontario


{VIDEO} Is It Safer To Smoke Weed Than Smoke Cigarettes?

We take a quick look at the difference between smoking cannabis and smoking cigarettes.

Check out the full article at: https://cannabis.wiki/cannabis...


-

The views and opinions expressed in this video are of the presenter and do not necessarily reflect the official policies or positions of JADEO.

JADEO makes no representations or warranties of any kind, express or implied, about the completeness, accuracy, reliability or suitability with respect to any content contained within the video.

JADEO urges you to consult with a qualified physician for consultation, diagnosis and/or treatment plans with respect to your medical condition(s) and/or wellness goals.

-



Stay informed. Stay connected.
#WeAreJadeo


Related comments

  • From Burge

    Sweet video

Cannabis Wiki Strains & Growing 1 month ago / London, Ontario


Complete guide to common cannabis pests and how to treat them

If you're curious about all the different pests your cannabis plants might bring or are looking to identify a particular insect, you've come to the right place. Follow along this guide to learn about some of the most common cannabis plant pests and how to get rid of them.


Check out the full guide and more at Cannabis Wiki.


Related comments

  • From Connor Christine

    Good to know.

  • From 22

    You should try interviewing the Master Grower Derek Pedro.... he has LOTS of knowledge in his head..

Cannabis Wiki Strains & Growing 1 month ago / London, Ontario


Here’s how to prevent deformed marijuana leaves

If you've ever had cannabis plants with leaves that have curled or become disheveled in some way, you know how frustrating it can be. So what is that's causing your plants to grow awry? Read on to learn some easily preventable causes of theses phenomenon.


Check out the full guide and more at Cannabis Wiki.

Related comments

Cannabis Wiki CannaBasics 1 month ago / London, Ontario


Making Cannabutter: Top 3 Cannabutter recipes

There are many benefits to making your very own cannabutter at home. Not only can you be 100% sure of the ingredients but it’s really easy!

Cannabutter is also one of the most versatile and healthy ways to ingest THC and CBD. No smoke or harmful chemicals and all the benefits. Cannabutter is used as the base of most edibles. From brownies and cookies to sauces and spreads.

Check out the top 3 cannabutter recipes at Cannabis Wiki

Related comments

  • From Janelle Simone

    ooooh this is good!

  • From Kenneth Joaquin

    Definitely trying this out.

Advertisement

JADEO CannaBasics 2 months ago / Toronto, Ontario


Top 3 Books That Break The Stigma

Life after prohibition is an uncharted landscape with lots of new opportunities to shift our culture to one with less stigma around the use of the cannabis plant. JADEO members may represent those of us who are pro-legalization, but what if you find yourself in conversations with prohibitionists? Having a very good grasp on the context of our new freedom with legalization could help you speak with any of these individuals, or with someone you love who could benefit from medicinal cannabis but fears how others may judge them. There is an entire history of cannabis to put into perspective when being an advocate or an informed friend, so we wanted to showcase a few books to pick up which help break the stigma around this important topic for JADEO members.

Busted

An Illustrated History of Drug Prohibition in Canada
By Susan Boyd

"Busted" by Susan Boyd

One of the lesser known books on cannabis topped our list because it’s specific to the history of cannabis prohibition in Canada. Busted is an illustrated history of Canadian drug prohibition that provides insights on the resistance to that prohibition. “Reproducing over 170 archival and contemporary drawings, paintings, photographs, film stills and official documents from the 1700s to the present, Susan Boyd shows how Canada’s drug prohibition policies evolved and were shaped by race, class and gender discrimination.” Her beautifully designed book demonstrates through a look into the history how prohibition and criminalization produces harm rather than benefits. The book acknowledges the arrest of thousands of Canadians each year for cannabis-related offences, and the current drug overdose crisis.

“Busted is a book that should be read by all those who wish to understand our convoluted drug policy. Combining historic and modern graphics with scientific facts, the book allows readers to grasp the insanity of drug laws.”

— Senator Larry Campbell

Brave New Weed: Adventures into the Uncharted World of Cannabis

By Joe Dolce

"Brave New World" by Joe Dolce

In Brave New Weed, former editor-in-chief of Details and Star, and author Joe Dolce, goes to Amsterdam, Israel, California, and Colorado, where he “skillfully unfolds the odd, shocking, and wildly funny history of this complex plant.” As he travels the globe he "tears down the cannabis closet" in an attempt to demystify this new frontier, seeking answers to the questions we didn’t know we should ask.

Looking back at the war on cannabis which has been waged in the United States since the early years of the twentieth century, society has undergone a massive shift in perspective since legalization has begun to catch fire, that is allowing us all to reconsider our beliefs. Dolce traces its history and possible future as he investigates the social, medical, legal, and cultural ramifications of this surprisingly versatile plant. As a result he paints “a fresh and much-needed portrait of cannabis, our changing attitudes toward it, and the brave new direction science and cultural acceptance are leading us.”

The Cannabis Manifesto

by Steve DeAngelo

"The Cannabis Manifesto" - by Steve DeANGELO

Steve DeAngelo, the founder of Harborside Health Center, the world's largest medical-cannabis dispensary, presents a compelling case for cannabis as a wellness catalyst that must become broadly legalized. In The Cannabis Manifesto he shares his view that there is no such thing as recreational cannabis use, challenging readers to rethink everything they thought they knew about cannabis.

A compelling overview of the state of cannabis today, DeAngelo explains how “prohibition has warped our most precious institutions—from the family, to the workplace, to the doctor’s office and the courtroom.” His book answers essential questions about the plant, using extensive research to fuel a thoughtful discussion about cannabis science and law, as well as its biological, mental, and spiritual effects on human beings.

Comment below and let us know your fave books for breaking the stigma.

Related comments

JADEO CannaBasics 3 months ago / Toronto, Ontario


The Entourage Effect: A Closer Look

There’s been a lot of buzz lately about a phenomenon called “the entourage effect,” but what is it?

The idea behind this effect is that when we combine compounds in their natural state we don’t end up with the sum of the parts but rather a multiplying effect. With cannabis, thousands of natural compounds within the plant interact together and with the human body to produce a more meaningful effect than what you’d experience with any single one of the compounds used alone.

This term “entourage effect” was only first introduced around the year 2000, by the Israeli chemist who first who first discovered THC as the main psychoactive component of cannabis. It’s discovery helps explain why different cannabis strains may have different effects depending on the individual. Since strains can differ vastly in their chemical profiles, they can cause an equally vast number of experiences.

Lack of clinical trial research has given rise to critics of the entourage effect who claim that it does not exist, but in fact, it’s very concept is rooted in the centuries-old practice of whole plant medicine. The basic concept is that the chemical compounds found in medicinal plants work together to help that plant to offer its own power to provide healing.

The entourage effect

In the original study, Rafael Mechoulam Mechoulam and fellow chemist Shimon Ben-Shabat examined the interactions between compounds in the cannabis plant and found that certain cannabinoids, which had no effect on their own, could be used to help other cannabinoids in the plant to work more effectively. Other studies since back this initial finding, yet the concept of “the entourage effect” somewhat surprisingly remains a debated topic.

There’s no debate however to Dr. Ethan Russo, who is a Seattle based board certified neurologist and has done immense research on psycho-pharmacology. Former president of the International Cannabinoid Research Society and a former Chairman for the International Association for Cannabinoid Medicines, after 20 years of clinical practice, Dr. Russo took a full-time consulting position with a company out of Britain that develops cannabis based pharmaceuticals.

Dr. Russo is recognized internationally for his research on cannabis compounds and their effects in the body. His research found that “complementary pharmacological activities that may strengthen and broaden clinical applications and improve the therapeutic index of cannabis extracts.” Through these findings he discovered “synergistic effects” between different compounds that enhance and boost each other when combined.

In this we recognize isolated cannabinoids as if each has a list of specific effects. All of Dr. Russo’s research suggests that these effects can be mitigated, or enhanced, when they are paired with other chemical compounds that naturally appear in whole-plant cannabis.

While THC and CBD may be the most famous cannabinoids, they are by no means the only ones. In fact, they’re just two among many important players within the cannabis plant that work together to produce a number of potential therapeutic effects. There are at least 113 known cannabinoids found in cannabis, which bind to receptors in the human body’s endocannabinoid system, specifically the CB1 and CB2 receptors.

If you closely inspect your cannabis flowers, you’ll notice they’re enrobed in a layer of crystal resin that’s sticky to the touch. These crystals house thousands of compounds, including these cannabinoids and a number of terpenes and flavonoids. If you take pure THC, which we know is the main psychoactive ingredient in cannabis, you’ll experience “a high that has no specific character, so that seems boring,” says Mowgli Holmes, a geneticist and founder of a cannabis genetics company Phylos Bioscience. What gives cannabis “character,” in his similar view, are the hundreds of other chemicals it contains.

So what are the hundreds of other chemicals cannabis can contain other than cannabinoids? Dr. Russo examined the benefits of using products containing certain cannabinoids with specific terpenes. Terpenes are essential oils that naturally occur and give cannabis plants distinctive aromas and flavors. His research revealed that terpenes “could produce synergy with respect to treatment of pain, inflammation, depression, anxiety, addiction, epilepsy, cancer, fungal and bacterial infections.”

There is still much research to be done however to determine how all these fascinating chemicals react on a molecular level. In a 2011 review published in the British Journal of Pharmacology, chemists found similar interactions between cannabinoids and terpenes.

It’s believed that when the terpenes remain in a cannabis based product, the benefits are magnified. Researchers discovered that a terpene, linalool, combined with a cannabinoid like CBD, could be used as an effective anti-anxiety medication. Whereas combining linalool with THC makes for a potent sedative, or combining the terpene alpha-pinene with THC helps to retain acetylcholine (a molecule that aids in memory retention) and could help to mitigate the short-term memory loss caused by THC.

The power of scent in the entourage effect seems like a never ending list of fascinating molecular combinations. Limonene is an energizing terpene that can alleviate depression symptoms. Beta- Caryophyllene is powerful in reducing inflammation throughout the body, including the gastrointestinal system. Myrcene has sedative effects which promote calmness and provide relief from anxiety. Linalool is also an anti-anxiety and capable of acting as an anti-microbial. Pinene combats cognitive and memory issues by increasing focus. Multiple terpenes can be used in conjunction to treat a variety of issues in a single dose.

So while whole plant products with terpenes and full spectrum cannabinoids have high efficiency and are more potent than using an isolated compound, we see THC and CBD isolated in clinically approved medications. The reason for this is largely due to the regulatory standards that surround modern medicine. In essence, isolated compounds are much easier to dose, measure and track than a compound found naturally in a plant.

Medicines which are approved in the U.S. by the FDA have to be standardized, meaning that every dose must contain an exact amount of THC, something which can be difficult to guarantee in smokable cannabis, which usually comes with a THC content range rather than an exact measurement. This is the same as what we see prescribed by most doctors in Canada, but thankfully that is changing as legalization pushes the advances of medicinal cannabis.

Isolating constituents from the rest of the components that make up the whole-cannabis plant may offer MDs precision in prescribing, but most anecdotal evidence proves the endocannabinoid system responds more favourably to a full flower cannabis experience.

Consider the drug Marinol, a synthetic form of THC available since the 1980s. It is known to be a good appetite stimulant, but it’s also known to make patients high and paranoid. “When you just stimulate the CB1 receptor with this pure molecule, it's very intoxicating and patients don't tolerate it very well,” says Adie Wilson-Poe, who researches cannabis for pain management at Washington University in St. Louis.

Drugs like Sativex, which combines THC with CBD, or even pure cannabis flower or extracts, and is known to be tolerated by patients much better. “We specifically see that CBD protects against the paranoia and anxiety and the racing heart that THC produces,” Wilson-Poe says.

For smokers, flower vapers, or those making their own edibles by infusing flower into fats, what you will be experience is essentially the entourage effect. In our recent #wcw feature with Katrina Malmqvist of Gräs, she explained how the entourage effect is present in her fat bomb micro dose edibles.

"Since cannabinoids are fat soluble, I began infusing cannabis into organic coconut oil, which I found to be the best carrier. What I discovered was what we call the entourage effect; a microdose with full flower infusion of just 3mg was giving such a beautiful effect. It is long lasting, and delivers this slow, wonderful elevation that I found really helped me deal with some postpartum anxiety I was experiencing."

Unlike the isolated compounds, the full flower infuses into the carrier oils and is delivered to the body to produce a “next-level” high. Find this fascinating? So do we. To educate yourself more on microdosing, terpenes or the endocannabinoid system visit our special interest groups.

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Fabrizio Rossi CannaBasics 3 months ago / Vancouver, British Columbia


2019 The year not for the faint of heart in Cannabis.

2018 was the end of prohibition and definitely changed the landscape of our society in several ways, not only in Canada but on the worldwide stage.

Several countries around the world have opened the doors to medicinal Cannabis, but specifically countries in Asia is proof the winds of change are on the horizon and within the western hemisphere countries like Mexico are well on their way to legalization. And let’s not forget the Hemp bill in the US changing the CBD category. We are in for another amazing year in 2019.

2018 definitely had a few speed bumps along the way for Cannabis in Canada but we finished the first year of legalization in a good spot to start 2019.

Retail Provincial frameworks are visible in all provinces. Even though we may not agree with some provincial regulations, we have a starting point, and with days from Vancouver opening its first retail outlet this category will be an exciting one to observe.

Supply shortages are definitely an everyday story in all provinces and with some suppliers taking advantage of supply and demand and charging as much as $13 per gram, this made things even more interesting. But I do believe most LPs are moving forward with true forecasting initiatives to make sure the production facilities are optimized within their supply chain.

Micro Cultivation movement is well on their way with over 30 applications already submitted in the system. The "authentic craft cannabis" segment will be a great one to observe this year as the Master growers showcase their passion, strains and abilities, and with regulations allowing new players to bring new strains no questions asked, we should see some exciting new things by the end of 2019.

Edibles the new opportunity for 2019 for processing facilities to make a name for themselves is definitely one of my favorites. This will be a huge piece of the market with edibles, drinkables and everything else in between joining the market.

Market reports and sales results will be not for the faint of heart to watch as the "story" won’t be as important as the true results and category leaders and innovators surface to claim their titles.

Overall, an exciting year ahead for all of us but as always I want to take a moment to say thank you to all of you for sharing this exciting industry with me and each other. Yes, we all compete with each other in one way or another, but most of us share wins and challenges with each other as we are all growing, learning and paving the way to create a great, responsible, environment friendly industry for a better medicinal and recreational Cannabis.

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  • From Janelle Simone

    Agreed! There have been a few bumps but we're doing something that has never been done on this level before so this is to be expected. What is exciting is how the industry is learning and progressing. 2019 and beyond will definitely see growth and opportunity.

JADEO CannaBasics 4 months ago / Toronto, Ontario


The Truth About Terpenes

Is it a skunk or is it a plant? The smell of cannabis if often associated with the pungent aroma of the skunk. However, the distinct smell of many plants, not just cannabis, is due to the presence of terpenes, aromatic non-psychoactive organic hydrocarbon compounds designed to attract pollinators and ward off predators –naturally occurring essential oils. There are about 120 known terpenes found in cannabis. They are secreted inside the tiny resin glands of cannabis flowers, producing a citrusy aroma in some strains, fruity and sweet accords in others and while some may invoke lavender fields, others can be more earthy and pungent. That signature skunkiness is due to the high presence of terpenes, namely myrcene, in varying quantities depending on the strain.

Terpenes are significant because, just as they have a specific smell, they colour and shape the specific effects of THC in cannabis, creating a unique “profile”: the difference between an active and elevating high as compared to a calming and sedating high is in part due to the terpenes within the strain and how they interact with THC. For example, the terpene Myrcene is thought to increase the effects of THC, induces sleepiness, and provides anti-inflammatory and analgesic effects. Limonene, another type of terpene, is thought to be an invigorating anti-depressant. Linalool is associated with arthritic symptoms and humulene may also reduce inflammation. Terpenes may enhance or mitigate the phototropic effects of THC and even affect receptors and neurotransmitters in the brain, akin to the way in which antidepressants function. There are a number of intersecting variables that contribute to the effects of cannabis and its properties, such as pain reduction, but the field is gaining a greater understanding of the role of terpenes. Researchers are working to determine exactly how each terpene works and how they interact with each other.

Understanding terpenes and their nuanced role in the usage and effect of cannabis has become a coveted skill when it comes to buying and growing cannabis, contributing to the rise of the cannabis sommelier and this burgeoning field. Particular strains are not only derived from the two major cannabinoids but also their terpene profile, as terpenes are critical both within the medical use of marijuana and for connoisseurs. Those cultivating the plant are paying an increasing amount of attention to terpenes as the market and the needs of users shift. By cross-breeding with an eye towards creating these layered profiles, they are now producing new strains geared towards certain ailments and manipulating them for taste, smell, and effect by using low-stress growing practices and other natural processes. Specialized dog trainers have even tapped into the olfactory skills of working canines to help sniff out terpenes that could be important factors in the use of cannabis, such as beta-caryophyllene, a powerful anti-inflammatory terpene. This aspect of cannabis horticulture is still developing and much more experimentation, mapping, and testing to identify more terpenes and important combinations, but this much is certain, there is much more to it than a roadside skunk!

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JADEO CannaBasics 5 months ago / Toronto, Ontario


"Elevated" Getaways For The Romantic At Heart

In the spirit of Valentine's day, we wanted to explore cannabis friendly travel accommodations to inspire romantic getaways in a new era post-legalization. While Canadians can now carry 30g of cannabis on them while traveling within Canada, they may not leave the country with it on their person. With that in mind, we took a look at noteworthy hotels in Canada that are promoting cannabis tourism and sussed out which attractive destinations are offering up cannabis-themed stays in nearby legal states. Here are a few of JADEO’s favourites:

British Columbia

Hotel Zed

Hotel Zed - British Columbia

Anyone who has been to Victoria or Kelowna might recognize the name Hotel Zed, a vibrantly themed facelifted motel chain toting a bright VW bus as their iconic symbol. Hotel Zed offers ‘Weed Walk Guides,’ highlighting neighbouring dispensaries, tips on local things to do, and great places to eat.

The Her(b) Life featured Hotel Zed at the dawn of legalization, describing how “its hip, neon-retro accouterments include working rotary dial phones in guestrooms, vinyl record listening and typewriter stations in every lobby – there are also Ping Pong lounges, Wii stations, mini-discos, free roller skate rentals, and vintage VW shuttle buses… making Weed Walk Guides the perfect addition.”

For cannabis lovers, this fun, retro hotel can provide a wealth of information about what to see and do (while high;) in BC., making for the kind of stay that won’t harsh your buzz.

Learn more at https://www.hotelzed.com/

US Destinations

With several US states firmly established in their legal framework, we’ve seen businesses arise in the travel sector, notably in Oregon and Colorado. Interested in heading south of the border for a cannabis-infused vacation? Make sure you don’t fly with any on you and consider one of the 420 friendly accommodations below.

Oregon

Jupiter Hotel, Portland

Jupiter Hotel - Portland, OR

Toted as Portland's original lifestyle boutique hotel, the Jupiter makes our list for offering the first ever cannabis-friendly package in Oregon. This optional add on to your stay includes a munchie kit, a vape pen, Dope Magazine swag, and coupons to nearby dispensaries to buy your own cannabis.

With a plethora of fun things to explore in and around Portland, booking into the Jupiter makes cannabis, not just a ‘synch’ but a celebration of sorts.

Learn more at: https://jupiterhotel.com/420-p...

Colorado

Bud + Breakfast Lodge, Denver

The first and only all-inclusive cannabis-friendly lodge is also located in Denver, Colorado. Just as the name imagines, residents are offered up strains at the lodge to smoke before breakfast. If this group stay this isn’t your cup of tea, a platform by the same name connects travelers with cannabis friendly owner listed accommodations, much like airbnb only with a 420 twist.

Magnolia Hotel, Denver

Magnolia Hotel - Denver, CO

The Magnolia is reported to be the best hotel in Denver of the few that allow vaporizing in-room. While cannabis tourism is huge in Colorado - most of the industry focused on tours, accommodations or other related cannabis experiences. Despite this influx of tourism in recent years, many commercial 420 friendly hotels are still defining their policies, or are hesitant to publicly market themselves as 420 friendly. Because of this, many people are choosing to rent their private bud and breakfast accommodations to cannabis-friendly guests.

Learn more at: https://magnoliahotels.com/den...

Global Travel

Billing itself as “the largest collection of marijuana-friendly hotels and other cannabis-friendly rentals anywhere on the web”, Bud and Breakfast features accommodations across the US with spots in Jamaica, Mexico, Spain, Uruguay, and Canada (which are mostly in Vancouver).

The website is essentially able to pair travelers with accommodations listed by welcoming 420 friendly property owners, regardless of the legal confines around cannabis in each location. For cannabis enthusiasts interested in going to locations outside of Canada, bud and breakfast can prove to be a wonderful way to explore other places with the guidance of a host who can help you navigate the framework of their local area.

Wherever you chose to travel, be sure to know your legal rights and mind the laws so you can fully enjoy your romantic getaway experience. Write to us if you can any tips for future features, particularly if you are staying in Canada and discover a great place to recommend to JADEO readers - we want to hear all about it!

-

Stay Informed. Stay Healthy
#WeAreJADEO

Related comments

  • From Kenneth Joaquin

    Great to know for frequent travellers/users!

  • From Janelle Simone

    hmmm...will def add a few of these to my list.

  • From tristan

    What about cannabis-friendly tour operators? High Definition Tours is based in Vancouver and ready to take you exploring!

    • From Burge

      That sounds exciting! Tell me more!

      • From tristan

        Cannabis tours are the next big thing and we're getting them started on the west coast! If you're ever coming out here to Vancouver and want a cannabis-friendly tour be sure to check out highdefinitiontours.com. Summer experiences coming soon!

Mike Robinson Medical Cannabis 6 months ago / Santa Barbara, Alberta


"Yes, I love Daddy" Genevieve's life forever changed by Cannabis

She stole my heart, she calls me Daddy:

Life with Genevieve has always been filled with love and so many happy times, it’s been an incredible journey I’m so happy to continue. Many in the world of Autism or with a child that has a developmental delay or with special needs would beg to differ in that this lifestyle is ‘the best in the world’. But, I wouldn’t change it for anything. Many times Anne Mari are up late at night/all night with her and many times things we’d like to do become very secondary due to her needs, but isn’t that the way it is with all kids? Why do people have to look at children such as Genevieve as ‘delayed’ and ‘difficult’ when kids with no disability at all can be a handful – getting in trouble quite often, lack manners or respect, desire to succeed, and have so much to say that’s hardly intelligible with new slang coming out by the day that many parents would pay for a mute button if at all possible! I type that as I laugh, knowing that as much as our kids can be overwhelming in one way they can also overwhelm us with love – and it doesn’t matter whether it’s a disabled child or not – Love is Love. I got the greeting of a lifetime after missing my girls so much while on the road.

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The love a children show can bring you to your knees in tears. Genevieve did that just last night. After being gone for 10 days I returned knowing that she was very happy watching video’s of her laughing away and smiling as her mom spoke of Daddy coming home. Often I wonder who it’s more difficult on when we are apart. The young teen that people think has no cognition of what’s going on or the adult that’s been alive for a half century that knows exactly what’s going on. By far, this child misses her daddy far more than any ‘Autism Expert’ would like to admit. As she came to greet me her Mom asked her “Did you miss Daddy” a hard head nod followed, I told her I loved her and kissed the side of her temple asking her “Do you love Daddy” – I didn’t expect a response as we’ve never gone into asking her about whether she loves anyone, it’s not generally an emotion displayed by the severely autistic. “Des” she vocalized with a head nod that was so intense. “Of course I love him” was how I interpreted it. Without a doubt it was one of those times in the world of special kids like her, or with any child for that matter, when you break out the Kleenex. Kids show the purest form of love there is, and to have it coming from a ‘non verbal’ severely autistic child? Wow, a moment I’ll never forget. Never…

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Generally we don’t see anywhere near that much empathy in severely autistic children. Genevieve also has Severe Intractable Epilepsy and as many know, like her Daddy, she uses Cannabis Oils for medicine. But she does vary from me quite a bit in that medication protocol. Unlike myself, Genevieve has been fully weaned off of ALL pharmaceuticals! These are exciting times as the beautiful and amazing Cannabis plant and it’s extracts relieve many of the necessity to use pharmaceuticals. We all know the risks but many aren’t aware that a vast majority of Rx Medications are known to be carcinogenic aka they cause Cancer. This isn’t a theory, it’s a proven fact as many are listed under the state of California’s well-known ‘prop 65 items known to the state to cause cancer’. Many other states have similar lists and laws that require signage at locations that carry any items known to cause cancer – except pharmacies. Why would they be excluded? A question I ask often but there’s never a reasonable answer.

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Back to Autism and Genevieve, her love is so intense. She’ll show us quickly who’s good and who’s not. It’s intense how she’ll literally show us who she wants to be around by how she’ll perform tasks and get her work done. What’s really intense is she seems to know who’s got the dark past and who doesn’t, and quickly. Children with Autism and adults as well are often discounted by society when indeed they are the masters of it! I know many people but I rarely hear from the Autistic adults I know in regards to who said what or who’s doing what, more so I’ll hear pertinent details of who, what, why, when, and where. It’s much easier to get the facts and straight up answers. Of course this is the high functioning crowd that many aren’t even aware are on the Autism Spectrum unless they let them know. With the younger more severe kids and adults, many especially at Genevieve’s find great difficulties in the ability to understand why others do what they do or even care, seemingly much more of a challenge to reach outside of self, after all that’s exactly what the word means. In ancient Greece the word ‘autos’ means self. Then in the late 1700’s the ‘ism’ was added which has a definition of: ‘a distinctive practice, system, or philosophy, typically a political ideology or an artistic movement’. It’s hard to look at the two words that create Autism and see a disability, rather I see many abilities that others do not and will never have.

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Genevieve continues to make progress and continues to turn the heads of those that did not believe Cannabis Oils would change her life or any others. She continues to be the face of change and has no care in the world about the who, what, where, when or why – she’ll leave that to us folks that over think things. We’re always worried about tomorrow and thinking of yesterday but for Genevieve it’s the here and now always. She’s taught me the biggest lesson in the world and that’s live for the day. We both have Epilepsy so I can use the words “Seize every moment you can of happiness and joy” without someone getting offended – we both use Cannabis oil and cannabinoid protocols to make sure those are moments of joy and not moments in the hospital!

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I still can’t believe how boldly she declared she loves her Daddy. She already had my heart.. I’d do anything to make her life better, and I’m working hard on that now. My goal? To buy her a carousel. Yes, the entire ride and a place to house it. I like to think small and work up to something bigger – like an amusement park just for her and other kids with Autism totally catered to their specific needs and not to the world abound that has all the places in the world to go to… We need to concentrate on those that need help and forget about what we personally need or want. Just leave yourself, there’s a certain freedom in that.

Thank you for reading,

Mike Robinson, Medicinal Cannabis Patient & Activist. But mostly? Genevieve’s Daddy

Director of Business Development – Cisbay Global, Inc. https://cisbay.com/ – Providing solutions for better agricultural growth and sustainability and paving the way to naturally clean our waterways and more across the globe.

“AN ECO-FRIENDLY WORLD BEGINS WITH HEALTHY SOIL AND CLEAN WATER.”

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Mike Robinson Health & Wellness 7 months ago / Santa Barbara, Alberta


Judge That Jailed People Over Cannabis Is Now A Patient In Need

By: Mike Robinson

Retired Judge Admits “Throwing People In Jail” For Cannabis Haunts Him After It Saved His Life:

Now here’s a new twist. The very same judge, Doug Bench, who used to put away those with minor marijuana offence without any qualms, came forward about how Cannabis saved his life in order to help the people of Florida and beyond learn the truth about prohibition. The success stories regarding cannabis are seemingly endless, and the medicinal properties of this plant when properly administered have proven to to have a tremendously positive effect on our health, so much that the healthcare and pharmaceutical industry could eventually be partially replaced – especially many of our prescription drugs. This isn’t necessarily a bad thing with knowledge we’ve all gained on both prescription drugs, which experts say in studies kill more than 100,000 people annually in the US alone, and the conventional treatments for Cancer and other illnesses that seem to make many of us even sicker than we were – or worse. When this former Judge found out that he could benefit from what he used to demonize? His mind changed quickly when his own life was on the line and that led to being a huge voice in the Florida push for approval of use of the whole plant without extensive restrictions.

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This whole recovery and this judge who has came forward in such a positive manner is a great example of a change in perspective, and in his case, a major paradigm shift. Something he once believed to be true was no longer true because of his own experience in dealing with Chronic Obstructive Pulmonary Disease. In the video below, he admits to throwing hundreds of people in jail for using this plant because “At the time I thought it was the right thing to do.”

When Bench was diagnosed with Chronic Obstructive Pulmonary Disease, or COPD, which can result in a slow and painful death, his life was saved after realizing the benefits of cannabis in treating his disease. Now, Bench has made it his life’s work to wake people up to the “70 years of lies” the US government has told the citizens about marijuana.

With so many fighting for their freedom across the country this is an amazing thing to see, and it doesn’t stop here – many others are reporting on Judge Doug Bench. Cannabis Health Radio did a special on this in mid 2017 in the push for the State’s full legalization of Cannabis.

Watch two videos on this here:

As A Judge He Put People In Jail For Cannabis, Now He Needs It and Talks on YouTube

The Judge Talks On Video

Prior to this 2018, the state of Florida was regarded as one of the worst possible states to be caught in possession of cannabis. According to a 2009 analysis by former NORML Director Jon Gettman, no state in this country punished people more severely for minor marijuana offenses than Florida. However, thanks in part to a former Florida judge, all this is gradually changing,

The huge American cannabis crop makes the growth Industry only 2nd to corn. That’s a huge move in such a short time. With former judges, athletes, Hollywood stars, and even lawmakers stepping forward for Cannabis – it seems the momentum just won’t stop. For us patients that’s a must. We need every last person like Former Judge Doug Bench to come forward and speak.

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This story has moved around a bit with not too much attention by the media and I’ve yet to blog on it. I thought it was very worthy after reviewing it today and thinking of all the people I know that have had to go to jail over the plant. Sitting here pondering the countless times in the past we did this or did that running compassion programs and so much more – it’s a wonder many of us didn’t end up in more trouble and sentenced by a Judge, who like Doug Bench, would someday need the very plant they saw as evil and put someone behind bars for.

I’m thankful for Doug Bench and hope more like him step up to the plate and admit they were wrong. Admit that the people are right and that we’ve been dealt with unjustly by a government that seems to do no wrong while it’s people die needing a plant that they have a patent on. There’s no smooth way to go around that fact.

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Many are learning the truth and the more we hear from patients like ourselves and people that support us, the better off we are.

Mike Robinson, Medicinal Cannabis Patient and Former Director, The American Academy of Cannabinoid Medicine. Founder, Global Cannabinoid Research Center

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